https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 The interaction between bacterial transcription factors and RNA polymerase during the transition from initiation to elongation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10634 Sat 24 Mar 2018 08:13:48 AEDT ]]> Identification of inhibitors of bacterial RNA polymerase https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26825 in silico screening of novel transcription inhibitors. Here, we describe our approach for the design and testing of small molecule transcription inhibitors that work by preventing the interaction between the essential transcription initiation factor σ and RNAP. With the appropriate structural information this approach can be easily modified to other essential protein-protein interactions.]]> Sat 24 Mar 2018 07:36:25 AEDT ]]>